02 August 2016 In Liver Disease

Alcohol consumption is often a comorbid condition in other chronic liver diseases. It has been shown to act in synergy to increase liver injury in viral hepatitis, hereditary hemochromatosis, and nonalcoholic fatty liver disease (NAFLD), leading to an increased risk of cirrhosis, hepatocellular carcinoma, and liver-related mortality. Data suggest that modest alcohol consumption may be inversely related to the risk of developing NAFLD and lower rates of progression of NAFLD to nonalcoholic steatohepatitis (NASH). This article reviews data on the relationship between alcohol consumption and other chronic liver diseases.

16 October 2015 In General Health

No available abstract for this article.

23 July 2015 In Drinking & Eating Patterns

PURPOSE: To estimate the prevalence of alcohol use at the age of 10-11 years and document variation by early sociodemographic and concurrent alcohol-specific risk factors.

METHODS: The Millennium Cohort Study is a prospective, nationally representative study of live births in the United Kingdom across 12 months. A random sample of electoral wards was stratified to adequately represent U.K. countries, economically deprived areas, and areas with high concentrations of Asian and Black British families. A total of 12,305 child-mother pairs provided self-report data at 9 months (mother's marital status, age, education, occupational level; child gender, ethnicity, country) and age 10-11 years (adolescent alcohol use and attitudes).

RESULTS: After adjusting for attrition and sampling design, 13.4% of 10- to 11-year-olds had had an alcoholic drink (more than few sips), 1.2% had felt drunk, and .6% had five or more drinks at a time. Odds of ever drinking were higher among boys (1.47, 95% confidence interval, 1.29-1.68) and lower among early adolescents who were Asian British (vs. white; .09, .05-.17) or Black British (.42, .29-.62). Beyond sociodemographic differences, more positive attitudes about alcohol were associated with greater odds of drinking (1.70, 1.51-1.91), feeling drunk (2.96, 2.07-4.24), and having five or more drinks (4.20, 2.66-6.61).

CONCLUSIONS: Alcohol use in the last year of primary school was identified but not common. Its use varied by sociodemographic groups; early adolescents with more positive alcohol attitudes had especially high risks of early alcohol initiation. Results support calls for increased surveillance and screening for very early drinking.

15 June 2015 In Drinking & Eating Patterns

OBJECTIVE: The consumption of alcohol mixed with energy drinks (AmEDs) is a form of risky drinking among college students, a population already in danger of heavy drinking and associated consequences. The goals of the current longitudinal study were to (a) identify types of AmED users between the first and second year of college and (b) examine differences among these groups in rates of highrisk drinking and consequences over time.

METHOD: A random sample of college student drinkers (n = 1,710; 57.7% female) completed baseline and 6-month follow-up measures assessing alcohol-related behaviors.

RESULTS: AmED use was endorsed by 40% of participants during the course of the study. As anticipated, four distinct groups of AmED users were identified (nonusers, initiators, discontinuers, and continuous users) and were significantly different from one another on drinking and consequence outcomes. Further, significant Time x Group interaction effects were observed for drinking and overall consequences. Generally, across all outcomes and time points, nonusers reported the lowest rates of drinking and consequences, whereas continuous users consistently reported the highest rates of drinking and consequences. Students who initiated AmED use during the course of the study also reported anabrupt increase in alcohol use and reported consequences.

CONCLUSIONS: Findings suggest students who consistently engage in and initiate AmED use also engage in riskier drinking behaviors and experience higher rates of consequences. Interventions that specifically target AmED use may be warranted and have the potential to reduce alcohol-related consequences.

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