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Updated information about scientific approaches and research field.

WHAT IS THE MOLI-SANI STUDY? The Moli-sani study (www.moli-sani.org) is a cohort study carried out in central/southern Italy aiming at evaluating the risk factors (environmental, genetics, bio-molecular) linked to chronic-degenerative disease with particular regard to cancer, cardiovascular, cerebrovascular and neurodegenerative disease. WHAT ARE THE LATEST FINDINGS OF THE MOLI-SANI STUDY? In this prospective study of 21.000 participants from a Mediterranean population, life-time abstainers and heavier consumers (>48g/day)* had higher rates of hospitalization for all causes compared to moderate drinkers, especially…
Tuesday, 05 February 2019 14:21

Update from the CASCADE study

WHAT IS THE CASCADE STUDY? The CASCADE study (CArdiovaSCulAr Diabetes & Ethanol) is the first randomized wine study with a focus on diabetes. 224 abstainers with type 2 diabetes were randomly assigned to consume 1 glass (150 ml) of red wine, white wine or water for 2 years, on top of a Mediterranean diet that was not restricted in terms of calories. WHAT IS THIS? The current publication, “Wine and health- new evidence” summarizes previous findings from the CASCADE study…
Tuesday, 05 February 2019 14:18

Wine and dementia

A new study with the title “Alcohol use and dementia: a systematic scoping review” published on 05/01/19 carried out a systematic review about the intake of alcoholic beverages and the risk of cognitive impairment. WHAT’S THE FRAME? Considering the increasing ageing of populations worldwide, cognitive impairment and dementia are expected to increase and create serious challenges for healthcare providers. The global number of individuals with dementia is projected to triple, from approximately 50 million in 2018 to 152 million in…
Over the last decades, observational studies have shown that individuals who abstain entirely from the consumption of alcoholic beverages might be worse off than moderate drinkers. Several recent studies have tried to discredit this J-shaped relationship between drinking and all-cause mortality, pointing to a ‘no-safe level’ of drinking. Wood and colleagues for example, challenge the long-standing conclusion that a glass of wine a day with the meals might lower the cardiovascular disease risk and could even be beneficial for the…
This meta-analysis examined the Mediterranean diet (MedDiet) of all published prospective studies, evaluated the relative contribution of individual components of this diet and how they relate to longevity or all-cause mortality. The results confirm an inverse association of the MedDiet and mortality, meaning that those individuals adhering the most to a MedDiet lived longer. When it comes to the individual components of the MedDiet, one of the major protective factors was moderate, non-excessive intake of alcoholic beverages –mostly in the…
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