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his critical review proposes to regard Mendelian Randomization (MR) as another type of observational study, not as an alternative to observational studies to determine causality. The researchers highlight the limitations of MR when applied to the associations of alcohol consumption with cardiovascular disease (1). MR is a method that is increasingly being used to conduct studies on alcoholic beverages and health and as result challenges the findings of previous research, such as the J-shaped curve. What does it mean: This…
In this publication, the evidence of observational and randomized controlled trials regarding the association between the Mediterranean diet (MD) and cancer as well as possible mechanisms involved, are assessed. The authors conclude that the Mediterranean diet (MD) seems clearly linked to preventing the development of cancer, as reported in observational studies and respective meta-analyses. Its individual components (fruits, vegetables, whole grains, legumes, nuts, fish, moderate wine consumption and a reduced intake of red/processed meat) have also been linked to cancer…
The current study findings support the idea that a healthy lifestyle, i.e. following a Mediterranean Diet (MD), which includes moderate wine consumption, should be the first option to avoid bone fractures. The prevention of bone mass loss and related complications associated with osteoporosis is a significant public health issue. The Mediterranean Diet (MD) is favourably associated with bone health, a potentially modifiable risk factor. The objective of the study was to determine the adherence to the MD in a sample…
There seems to be an increasing scientific interest in wine polyphenols and their influence on the gut microbiota. The authors of this publication look at the current evidence regarding the relationship between red wine polyphenols and their influence on the gut microbiota. Various red wine polyphenols including flavonoids (i.e. anthocyanins), non-flavonoids (stilbenes), catechins, etc. are supposed to exhibit positive health effects by reducing the oxidative stress in the body and promoting beneficial gut bacteria. Once digested, relatively small amounts of…
This prospective Danish study examined the influence of wine consumption during adolescence on the weight gain until midlife. The results show that among non-smoking adolescents (average age at baseline 17 years), alcohol and particular wine consumption seems to be related to less weight gain until midlife during the 20 year follow-up period. The researchers conclude that whether this may be related to a specific lifestyle, including a health diet and habits associated with wine and drinking of alcoholic beverages during…
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