General Health

Moderate wine drinkers have a lower risk to die from any cause (lower total  mortality risk) than those who abstain or drink heavily. This widely accepted association is known as the J-curve. This J-curve is attributable to the beneficial effect on cardiovascular health which compensates the negative effects of some cancers resulting in a lower risk to die from any possible cause. The relative risk of dying is lowest among light to moderate drinkers and increased among abstainers. However, the risk increases dramatically with each drink above moderation. Thus, while one or two glasses can be considered “good for your health”, drinking more than what guidelines suggest will not provide more benefits, only more harm.

 

If consumed in excess, alcoholic beverages increase the exposure to a wide range of risk factors whereby the risk rises with the amount of alcohol consumed. Thus, it is crucial to prevent abusive consumption. Alcohol abuse is associated with a range of long-term chronic diseases that reduce the quality of life. These include hypertension, cardiovascular problems, cirrhosis of the liver, alcohol dependence, various forms of cancer, alcohol-related brain damage and a range of other problems. Not only the amount of alcohol but also the drinking patterns are important. Findings from a meta analysis support results from other studies that binge drinking is detrimental to heart health. The authors concluded that it is best for drinkers to avoid binge drinking -- not only because of the possible heart effects, but also because of more immediate risks, like accidents and violence.

 

In addition to health issues resulting from excessive alcohol consumption, there are social consequences, both for the drinker and for others in the community. The consequences include harm to family members (including children), to friends and colleagues as well as to bystanders and strangers.

 

The above summary provides an overview of the topic, for more details and specific questions, please refer to the articles in the database.

 

 

Cardiovascular disease (CVD) risk factors, incidence and death increases from around the time of menopause comparing to women in reproductive age. A healthy lifestyle can prevent CVD, but it is unclear which lifestyle factors may help maintain and improve cardiovascular health for women after menopausal transition. We conducted a systematic review and meta-analysis of prospective cohort studies to evaluate the association between modifiable lifestyle factors (specifically smoking, physical activity, alcohol intake, and obesity), with CVD and mortality in middle-aged and elderly women. Pubmed, Embase, among other databases and reference lists were searched until February 29th, 2016. Study specific relative risks (RR) were meta-analyzed using random effect models. We included 59 studies involving 5,358,902 women. Comparing current versus never smokers, pooled…
Background -Americans have a shorter life expectancy compared with residents of almost all other high-income countries. We aim to estimate the impact of lifestyle factors on premature mortality and life expectancy in the US population. Methods -Using data from the Nurses' Health Study (1980-2014; n=78 865) and the Health Professionals Follow-up Study (1986-2014, n=44 354), we defined 5 low-risk lifestyle factors as never smoking, body mass index of 18.5 to 24.9 kg/m(2), >/=30 min/d of moderate to vigorous physical activity, moderate alcohol intake, and a high diet quality score (upper 40%), and estimated hazard ratios for the association of total lifestyle score (0-5 scale) with mortality. We used data from the NHANES (National Health and Nutrition Examination Surveys; 2013-2014) to…
BACKGROUND: Findings from studies of alcohol and obesity measures (eg, waist circumference [WC] and body mass index [BMI; calculated as kg/m(2)]) are conflicting. Residual confounding by dietary intake, inconsistent definitions of alcohol consumption across studies, and the inclusion of former drinkers in the nondrinking comparison group can contribute to the mixed literature. OBJECTIVE: This study examines associations of alcoholic beverage consumption with dietary intake, WC, and BMI. DESIGN: Cross-sectional data from the 2003-2012 National Health and Nutrition Examination Survey were analyzed. PARTICIPANTS/SETTING: Adults 20 to 79 years of age (n=7,436 men; n=6,939 women) were studied. MAIN OUTCOME MEASURES: Associations of alcoholic beverage consumption with energy (kcal), macronutrient and sugar intakes (% kcal), WC, and BMI were determined. STATISTICAL ANALYSES PERFORMED:…
BACKGROUND: Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. METHODS: We did a combined analysis of individual-participant data from three large-scale data sources in 19 high-income countries (the Emerging Risk Factors Collaboration, EPIC-CVD, and the UK Biobank). We characterised dose-response associations and calculated hazard ratios (HRs) per 100 g per week of alcohol (12.5 units per week) across 83 prospective studies, adjusting at least for study or centre, age, sex, smoking, and diabetes. To be eligible for the analysis, participants had to have information recorded about their alcohol consumption amount…
OBJECTIVES: To investigate the association between alcohol consumption and left ventricular (LV) function in a population with low average alcohol intake. DESIGN, SETTING AND PARTICIPANTS: A total of 1296 healthy participants, free from cardiovascular diseases, were randomly selected from the third wave of the Norwegian HUNT study (2006-2008) and underwent echocardiography. After validation of the inclusion criteria, 30 participants were excluded due to arrhythmias or myocardial or valvular pathology. Alcohol consumption, sociodemographic and major cardiovascular risk factors were assessed by questionnaires and clinical examination in the HUNT3. General linear models were used to analyse the cross-sectional associations between alcohol intake and LV indices. PRIMARY AND SECONDARY OUTCOME MEASURES: LV functional and structural indices were measured with tissue Doppler and speckle…
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