General Health

Moderate wine drinkers have a lower risk to die from any cause (lower total  mortality risk) than those who abstain or drink heavily. This widely accepted association is known as the J-curve. This J-curve is attributable to the beneficial effect on cardiovascular health which compensates the negative effects of some cancers resulting in a lower risk to die from any possible cause. The relative risk of dying is lowest among light to moderate drinkers and increased among abstainers. However, the risk increases dramatically with each drink above moderation. Thus, while one or two glasses can be considered “good for your health”, drinking more than what guidelines suggest will not provide more benefits, only more harm.

 

If consumed in excess, alcoholic beverages increase the exposure to a wide range of risk factors whereby the risk rises with the amount of alcohol consumed. Thus, it is crucial to prevent abusive consumption. Alcohol abuse is associated with a range of long-term chronic diseases that reduce the quality of life. These include hypertension, cardiovascular problems, cirrhosis of the liver, alcohol dependence, various forms of cancer, alcohol-related brain damage and a range of other problems. Not only the amount of alcohol but also the drinking patterns are important. Findings from a meta analysis support results from other studies that binge drinking is detrimental to heart health. The authors concluded that it is best for drinkers to avoid binge drinking -- not only because of the possible heart effects, but also because of more immediate risks, like accidents and violence.

 

In addition to health issues resulting from excessive alcohol consumption, there are social consequences, both for the drinker and for others in the community. The consequences include harm to family members (including children), to friends and colleagues as well as to bystanders and strangers.

 

The above summary provides an overview of the topic, for more details and specific questions, please refer to the articles in the database.

 

 

The passage of time dictates the pace at which humans and other organisms age but falls short of providing a complete portrait of how environmental, lifestyle and underlying biological processes contribute to senescence. Two fundamental features of the human experience that change dramatically across the lifespan include social interactions and, for many, patterns of alcohol consumption. Rodent models show great utility for understanding complex interactions among aging, social behavior and alcohol use and abuse, yet little is known about the neural changes in late aging that contribute to the natural decline in social behavior. Here, we posit that aging-related neuroinflammation contributes to the insipid loss of social motivation across the lifespan, an effect that is exacerbated by patterns of repeated…
Epidemiological estimates indicate not only an increase in the proportion of older adults, but also an increase in those who continue moderate alcohol consumption. Substantial literatures have attempted to characterize health benefits/risks of moderate drinking lifestyles. Not uncommonly, reports address outcomes in a single outcome, such as cardiovascular function or cognitive decline, rather than providing a broader overview of systems. In this narrative review, retaining focus on neurobiological considerations, we summarize key findings regarding moderate drinking and three health domains, cardiovascular health, Type 2 diabetes (T2D), and cognition. Interestingly, few investigators have studied bouts of low/moderate doses of alcohol consumption, a pattern consistent with moderate drinking lifestyles. Here, we address both moderate drinking as a lifestyle and as an acute…
PURPOSE: The health benefits of the Mediterranean diet (MedDiet) have been widely studied. However, controversy remains for one of its components: alcohol intake. We aimed to assess the joint effect of adherence to the MedDiet and alcohol-drinking pattern on all-cause mortality. METHODS: We used data from 20,506 subjects from a prospective cohort of Spanish university graduates, the Seguimiento Universidad de Navarra (SUN) cohort. Adherence to the MedDiet was operationalized using four different dietary indexes and then categorized in low or high adherence, according to the median score. Alcohol-drinking pattern was evaluated with the previously defined the Mediterranean alcohol-drinking pattern (MADP), grouped into three categories of adherence (low, moderate and high adherence) and a fourth category for abstainers. The outcome was…
Understanding the associations between types of alcoholic drinks and adiposity has public health relevance, considering that adult overweight and obesity prevalence are increasing worldwide. We aimed to evaluate the association between overall alcohol consumption and types of alcohol drinks with markers of adiposity from the UK Biobank baseline data (n = 280,183, 48.3% female). G eneralized linear models were used to examine the associations between alcohol consumption with body mass index (BMI) and body fat percentage. Those drinking within the public health guidelines had a lower BMI by 1.34 kg/m(2) (95% CI 1.42, 1.26 kg/m(2)) compared to never drinkers. Association between alcohol consumption and body fat percentage were not statistically significant. Compared to those who never drink wines (red wine,…
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