Purpose To examine the associations of alcohol consumption with glaucoma and related traits, to assess whether a genetic predisposition to glaucoma modified these associations, and to perform Mendelian randomization (MR) experiments to probe causal effects.
Design Cross-sectional observational and gene–environment interaction analyses in the UK Biobank. Two-sample MR experiments using summary statistics from large genetic consortia. Participants
Stuart, Kelsey V.;Luben, Robert N.;Warwick, Alasdair N.;Madjedi, Kian M.;Patel, Praveen J.;Biradar, Mahantesh I.;Sun, Zihan;Chia, Mark A.;Pasquale, Louis R.;Wiggs, Janey L.;Kang, Jae H.;Kim, Jihye;Aschard, Hugues;Tran, Jessica H.;Lentjes, Marleen A. H.;Foster, Paul J.;Khawaja, Anthony P.;Aschard, Hugues;Chia, Mark;Chua, Sharon;Do, Ron;Foster, Paul;Kang, Jae;Kastner, Alan;Khawaja, Anthony;Kim, Jihye;Lentjes, Marleen;Luben, Robert;Madjedi, Kian;Montesano, Giovanni;Pasquale, Louis;Stuart, Kelsey;Warwick, Alasdair;Wiggs, Janey;Allen, Naomi;Aslam, Tariq;Atan, Denize;Barman, Sarah;Barrett, Jenny;Bishop, Paul;Black, Graeme;Braithwaite, Tasanee;Carare, Roxana;Chakravarthy, Usha;Chan, Michelle;Chua, Sharon;Day, Alexander;Desai, Parul;Dhillon, Bal;Dick, Andrew;Doney, Alexander;Egan, Cathy;Ennis, Sarah;Foster, Paul;Fruttiger, Marcus;Gallacher, John;Garway-Heath, David;Gibson, Jane;Guggenheim, Jeremy;Hammond, Chris;Hardcastle, Alison;Harding, Simon;Hogg, Ruth;Hysi, Pirro;Keane, Pearse;Khaw, Peng Tee;Khawaja, Anthony;Lascaratos, Gerassimos;Littlejohns, Thomas;Lotery, Andrew;Luthert, Phil;MacGillivray, Tom;Mackie, Sarah;McGuinness, Bernadette;McKay, Gareth;McKibbin, Martin;Moore, Tony;Morgan, James;O'Sullivan, Eoin;Oram, Richard;Owen, Chris;Patel, Praveen;Paterson, Euan;Peto, Tunde;Petzold, Axel;Pontikos, Nikolas;Rahi, Jugnoo;Rudnicka, Alicja;Sattar, Naveed;Self, Jay;Sergouniotis, Panagiotis;Sivaprasad, Sobha;Steel, David;Stratton, Irene;Strouthidis, Nicholas;Sudlow, Cathie;Sun, Zihan;Tapp, Robyn;Thomas, Dhanes;Trucco, Emanuele;Tufail, Adnan;Viswanathan, Ananth;Vitart, Veronique;Weedon, Mike;Williams, Katie;Williams, Cathy;Woodside, Jayne;Yates, Max;Yip, Jennifer;Zheng, Yalin;Aung, Tin;Burdon, Kathryn;Chen, Li;Cheng, Ching-Yu;Craig, Jamie;Cree, Angela;de Vries, Victor;Driessen, Sjoerd;Fingert, John;Foster, Paul;Gharahkhani, Puya;Hammond, Christopher;Hayward, Caroline;Hewitt, Alex;Hysi, Pirro;Jansonius, Nomdo;Jonansson, Fridbert;Jonas, Jost;Kass, Michael;Khawaja, Anthony;Khor, Chiea;Klaver, Caroline;Koh, Jacyline;Lotery, Andrew;MacGregor, Stuart;Mackey, David;Mitchell, Paul;Pang, Calvin;Pasquale, Louis;Pasutto, Francesca;Pfeiffer, Norbert;Polašek, Ozren;Ramdas, Wishal;Schuster, Alexander;Segrè, Ayellet;Stefansson, Einer;Stefánsson, Kári;Thorleifsson, Gudmar;Thorsteinsdottir, Unnur;van Duijn, Cornelia;Vergroesen, Joëlle;Viswanathan, Ananth;Vitart, Veronique;Vithana, Eranga;Wiggs, Janey;Wilson, James;Wojciechowski, Robert;Wong, Tien;Young, Terri
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