Alcohol consumption appears to protect against non-alcoholic fatty liver disease

Background: Moderate alcohol consumption may have certain beneficial effects against non-alcoholic fatty liver disease, which is associated with metabolic syndrome. Aim To determine the association between drinking pattern and fatty liver in Japanese men and women.

Methods: A cross-sectional study was performed with health checkup data including information concerning alcohol consumption and ultrasonographic assessment of fatty liver.

Results: We analysed 4957 men and 2155 women without reported liver diseases (median age, 49 years). In men, 40% of nondrinkers and 28% of drinkers had fatty liver. Alcohol consumption was inversely associated with fatty liver (adjusted odds ratio, 0.54; 95% confidence interval, 0.46-0.63). The prevalence of fatty liver in each category of drinking frequency was 38% (1-3 days/week), 29% (4-6 days/week), and 24% (daily drinking); there was a significant inverse correlation between drinking frequency and the prevalence of fatty liver (P < 0.001). In women, 16% of nondrinkers and 10% of drinkers had fatty liver. Drinking less than 20 g on 1-3 days/week was associated with low prevalence of fatty liver (adjusted odds ratio, 0.47; 95% confidence interval, 0.23-0.96).

Conclusions: Alcohol consumption appears to protect against non-alcoholic fatty liver disease.

Additional Info

  • Authors:

    Moriya,A.; Iwasaki,Y.; Ohguchi,S.; Kayashima,E.; Mitsumune,T.; Taniguchi,H.; Ikeda,F.; Shiratori,Y.; Yamamoto,K.

  • Issue: Aliment.Pharmacol.Ther.
  • Published Date: 2010/12/1
  • More Information:

    For more information about this abstract, please contact
    This email address is being protected from spambots. You need JavaScript enabled to view it. at the Deutsche Weinakademie GmbH

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