Lifetime Alcohol Consumption and Risk of Barrett's Esophagus

OBJECTIVES:Alcohol is a carcinogen that may increase the risk of Barrett's esophagus (BE) through direct contact with esophageal mucosa. However, few studies have investigated this association and findings have been inconsistent. We sought to examine the association between measures of total and beverage-specific alcohol consumption and BE risk.METHODS:We conducted a large population-based case-control study that collected information on lifetime alcohol consumption and other exposures from 285 patients with nondysplastic BE, 108 patients with dysplastic BE, and two separate control groups: 313 endoscopy patients with acute inflammatory changes ("inflammation controls") and 644 population controls. We calculated odds ratios (ORs) and 95% confidence intervals (CIs) for categories of average alcohol consumption using unconditional multivariate logistic regression.RESULTS:Relative to life-long nondrinkers and consumption of

Additional Info

  • Authors:

    Thrift,A.P.; Pandeya,N.; Smith,K.J.; Mallitt,K.A.; Green,A.C.; Webb,P.M.; Whiteman,D.C.

  • Issue: Am.J.Gastroenterol.
  • Published Date: 2011/3/22
  • More Information:

    For more information about this absctract, please contact
    This email address is being protected from spambots. You need JavaScript enabled to view it. at the Deutsche Weinakademie GmbH

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